Distribution of Choline Acetylase in Insect Conductive Tissue

Biological Significance of Choline Acetylase **

Effects of Sex Steroids on the Choline Acetylase Activity in the Hypothalamus of Female Rats.

The central nervous system, especially the hypothalamus, exerts an influence on the gonadotropin secretion from the anterior pituitary, resulting in the stimulation of gonads. The sex steroids, in turn, react back on the central nervous system in order to adjust the anterior pituitary function for reproductive cycles (Harris, 1955a). As reported in the previous paper (Kobayashi et al., 1963), t...

Quantitative determination of choline acetylase, acetylcholine, and acetylcholinesterase in the developing rabbit cornea.

Components of the cholinergic nervous system, acetyl choline (ACh), choline acetyltransferase (ChAc), and acetylcholinesterase (AChE) have been measured quantitatively in the developing rabbit cornea. ACh was detected initially approximately 10 days after birth, and subsequently increased in a nonlinear fashion to attain adult levels approximately 50 days after birth. ChAc was found initially a...

Intracellular distribution of choline oxidase.

Recently considerable attention has been centered upon the relation of choline oxidase activity to folic acid, the Leuconostoc citrovorum factor (LCF), ascorbic acid, and vitamin B,,. From this laboratory it has been indicated that rat liver choline oxidase can be stimulated in vitro under certain conditions by these factors, especially if the activity of the enzyme is previously decreased by d...

Studies on Choline Acetylase Iv. Effect of Citric Acid* by David Nachmansohn

Previous investigations have revealed that the formation of acetylcholine by the enzyme choline acetylase requires for maximum activity, in addition to the protein moiety, the following components: K+, Mg++, adenosine triphosphate (ATP), a coenzyme, cysteine, and eserine (l-5). The coenzyme, described simultaneously by Nachmansohn and Berman and Lipmann and Kaplan (5, 6), contains apparently pa...